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Stanislava Stosic-Grujicic Selected Research

saquinavir-NO

10/2015The NO-modified HIV protease inhibitor as a valuable drug for hematological malignancies: Role of p70S6K.
10/2012Therapeutic potential of nitric oxide-modified drugs in colon cancer cells.
8/2012Unique antineoplastic profile of Saquinavir-NO, a novel NO-derivative of the protease inhibitor Saquinavir, on the in vitro and in vivo tumor formation of A375 human melanoma cells.
3/2012Saquinavir-NO-targeted S6 protein mediates sensitivity of androgen-dependent prostate cancer cells to TRAIL.
7/2011Cytotoxic and immune-sensitizing properties of nitric oxide-modified Saquinavir in iNOS-positive human melanoma cells.
2/2011In vitro and in vivo anticancer action of Saquinavir-NO, a novel nitric oxide-derivative of the protease inhibitor saquinavir, on hormone resistant prostate cancer cells.
5/2009The antitumor properties of a nontoxic, nitric oxide-modified version of saquinavir are independent of Akt.

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Stanislava Stosic-Grujicic Research Topics

Disease

9Type 1 Diabetes Mellitus (Autoimmune Diabetes)
12/2019 - 07/2005
9Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
09/2013 - 09/2002
8Autoimmune Diseases (Autoimmune Disease)
01/2018 - 07/2005
7Neoplasms (Cancer)
12/2015 - 05/2009
5Infections
07/2012 - 08/2010
4Hyperglycemia
07/2016 - 07/2005
4Multiple Sclerosis
09/2008 - 09/2002
3Glucose Intolerance
09/2014 - 08/2012
3Melanoma (Melanoma, Malignant)
08/2012 - 09/2008
2Type 2 Diabetes Mellitus (MODY)
12/2012 - 08/2012
2Prostatic Neoplasms (Prostate Cancer)
03/2012 - 02/2011
2Aspergillosis
09/2011 - 01/2011
2Inflammation (Inflammations)
01/2009 - 03/2007
2Demyelinating Diseases (Demyelinating Disease)
04/2008 - 04/2003
1Breast Neoplasms (Breast Cancer)
12/2015
1Hematologic Neoplasms (Hematological Malignancy)
10/2015
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
10/2015
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
10/2015
1Colonic Neoplasms (Colon Cancer)
10/2012
1Carcinogenesis
08/2012
1Weight Gain
08/2012
1Insulin Resistance
08/2012
1Obesity
08/2012
1Hepatitis
08/2009
1Experimental Melanoma
05/2009
1Drug-Related Side Effects and Adverse Reactions
05/2009
1Nervous System Diseases (Neurological Disorders)
01/2009
1Central Nervous System Diseases (CNS Diseases)
12/2007
1Pleurisy (Pleuritis)
06/2007
1Arthritis (Polyarthritis)
06/2007

Drug/Important Bio-Agent (IBA)

11CytokinesIBA
12/2015 - 07/2005
7saquinavir-NOIBA
10/2015 - 05/2009
7Macrophage Migration-Inhibitory FactorsIBA
08/2013 - 07/2005
6Pharmaceutical PreparationsIBA
10/2015 - 09/2002
5Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2012 - 08/2006
5Saquinavir (Invirase)FDA Link
10/2012 - 05/2009
4Ribavirin (Virazole)FDA LinkGeneric
01/2009 - 04/2003
3Streptozocin (Streptozotocin)FDA Link
01/2017 - 03/2007
3Proteins (Proteins, Gene)FDA Link
04/2012 - 07/2005
33-phenyl-4,5-dihydro-5-isoxazole acetic acidIBA
09/2008 - 03/2007
2HIV Protease InhibitorsIBA
10/2015 - 05/2009
2Carbon MonoxideIBA
05/2015 - 05/2014
2Insulin (Novolin)FDA Link
09/2014 - 08/2013
2GlucocorticoidsIBA
08/2013 - 01/2009
2Antineoplastic Agents (Antineoplastics)IBA
08/2012 - 08/2009
2Protease Inhibitors (Protease Inhibitor)IBA
08/2012 - 02/2011
2methyl acetateIBA
09/2011 - 07/2005
2Interleukin-4 (Interleukin 4)IBA
01/2011 - 08/2010
2Interleukin-17 (Interleukin 17)IBA
08/2010 - 08/2006
2tiazofurinIBA
04/2008 - 09/2002
1Tretinoin (Retinoic Acid)FDA LinkGeneric
12/2019
1Transforming Growth Factors (Transforming Growth Factor)IBA
12/2019
1IronIBA
01/2018
1Plant ExtractsIBA
07/2016
1Caspase 3 (Caspase-3)IBA
12/2015
1RutheniumIBA
12/2015
1Cisplatin (Platino)FDA LinkGeneric
12/2015
14-cymene (p-cymene)IBA
12/2015
12,2'-dipyridylamineIBA
12/2015
170-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA
10/2015
1AntioxidantsIBA
03/2015
1sodium boranocarbonateIBA
05/2014
1apotransferrinIBA
09/2013
1Interleukin-2 (IL2)IBA
09/2013
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
08/2013
1PhytochemicalsIBA
01/2013
1Antiviral Agents (Antivirals)IBA
10/2012
1Acetic Acid (Vinegar)FDA LinkGeneric
10/2012
1Nonesterified Fatty Acids (NEFA)IBA
08/2012
1Palmitic Acid (Hexadecanoic Acid)IBA
08/2012
1Glucose (Dextrose)FDA LinkGeneric
08/2012
1Triglycerides (Triacylglycerol)IBA
08/2012
12,2'- (hydroxynitrosohydrazono)bis- ethanamineIBA
08/2012
1AndrogensIBA
03/2012
1Hormones (Hormone)IBA
02/2011
1InterferonsIBA
01/2011
1Messenger RNA (mRNA)IBA
08/2010
1CaspasesIBA
04/2010
15'-Nucleotidase (5' Nucleotidase)IBA
09/2009
1EnzymesIBA
09/2009
1Apyrase (ATP Diphosphatase)IBA
09/2009
1purineIBA
09/2009
1N- acetyl- S- (alpha- methyl- 4- (2- methylpropyl)benzeneacetyl)cysteine 4-(nitrooxy)butyl esterIBA
08/2009
1Concanavalin AIBA
08/2009
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
05/2009
1SteroidsIBA
01/2009
1PurinesIBA
01/2009
1Adenosine Triphosphate (ATP)IBA
01/2009
1Adenosine Monophosphate (AMP)IBA
01/2009
1Adenosine Diphosphate (ADP)IBA
01/2009
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
06/2008
1AntibodiesIBA
06/2008
1Therapeutic UsesIBA
04/2008
1Collagen Type II (Type II Collagen)IBA
06/2007
1CarrageenanIBA
06/2007
1Interferon-gamma (Interferon, gamma)IBA
03/2007

Therapy/Procedure

5Therapeutics
07/2016 - 04/2003
1Oral Administration
01/2017
1Ligation
04/2012
1Drug Therapy (Chemotherapy)
05/2009